Browsing by Subject "DNA Repair"

Now showing items 1-2 of 2

    • ANCIENT SRAP DOMAIN SHIELDS ABASIC SITES TO PROMOTE GENOME INTEGRITY 
      Thompson, Petria Salewa; 0000-0002-3839-4303 (2020-06-02)
      Department: Biochemistry
      Abasic (AP) sites are one of the most common DNA lesions that can block replicative polymerases. Currently, all known mechanisms for AP site repair function within the context of double-stranded DNA (dsDNA). A newly ...
    • Mechanisms of DNA Translocases in the Repair of Damaged Replication Forks 
      Badu-Nkansah, Akosua Agyeman (2016-07-21)
      Department: Biochemistry
      Genomic replication is a highly challenging task. The DNA replication machinery must precisely duplicate billions of base pairs while tolerating a multitude of obstacles including damaged DNA, collisions with transcriptional ...