Browsing by Subject "T cells"
Now showing items 1-10 of 10
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(Vanderbilt University. Institute for Global Health, 2008-08-20)
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(2018-03-29)Department: Microbiology and ImmunologyThe immune system is a complex network of cells spread throughout the body, spanning dozens of tissue types and locations. A complete understanding of a systemic immune response, like those required for the regression of ...
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(2006-05-18)Department: Microbiology and ImmunologyAutoimmune and atopic diseases are immune-mediated multigenic diseases. The work of this thesis tests the hypothesis of performing gene expression profiling using peripheral blood mononuclear cells as a common source to ...
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(2007-08-02)Department: Biomedical EngineeringT cells occupy a central role in cell-mediated immunity and as such, deciphering the signaling events that govern T cell activity is critical in fully understanding the adaptive immune response. Current immunologic ...
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(2005-03-24)Department: Microbiology and ImmunologyThe differentiation of naive T helper (Th) cells into effector/memory subsets and their interaction with invading pathogens ultimately determines the outcome of infectious human diseases. The research detailed herein is ...
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(2019-03)The gastric bacterium Helicobacter pylori causes a persistent infection that is directly responsible for gastric ulcers and gastric cancer in some patients and protective against allergic and other immunological disorders ...
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(2009-03-31)Department: Microbiology and ImmunologyApolipoprotein B mRNA-editing complex 3G and 3F (APOBEC3G, A3G, A3F) reduce endogenous retrotransposition and also limit the replication of HIV-1. These cytidine deaminases have anti-HIV activity when packaged into virions, ...
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(2023-07-18)Department: Cancer BiologyT cells recognize several types of antigens in tumors, including aberrantly expressed, non-mutated proteins (self/shared-antigens; SSA) and mutated proteins or oncogenic viral proteins (tumor-specific antigens; TSA). ...
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(2023-07-18)Department: Cancer BiologyT cells recognize several types of antigens in tumors, including aberrantly expressed, non-mutated proteins (self/shared-antigens; SSA) and mutated proteins or oncogenic viral proteins (tumor-specific antigens; TSA). ...
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(2016-11-11)Department: Microbiology and ImmunologyThis thesis advances our understanding of circulating B and pTFH cells in untreated chronic HIV+ infection. My studies determined the frequency, phenotype, and functional response to antigen stimulation of pTFH and B cells ...