Browsing by Subject "alkylpurine"

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    • Structural and Biochemical Studies of Alkylpurine DNA Glycosylase AlkD 
      Rubinson, Emily Holtzman (2011-02-17)
      Department: Chemical and Physical Biology
      Alkylating agents covalently modify DNA bases to generate a chemically diverse set of lesions including cytotoxic N3-methyladenine (3mA) bases and mutagenic 1,N6-ethenoadenine (εA) and N7-methylguanine (7mG). To maintain ...