Browsing by Subject "allosteric"
Now showing items 1-3 of 3
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(2015-07-15)Department: PharmacologyThe essential roles of glutamatergic signaling in both normal and impaired cognitive functioning have caused metabotropic glutamate (mGlu) receptors to become targets of interest for the treatment of psychiatric disorders. ...
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(2014-07-22)Department: Chemical and Physical BiologyThe muscarinic acetylcholine receptors (mAChRs) are a family of G protein-coupled receptors comprised of five subtypes (M1-5) expressed throughout the central nervous system (CNS). These receptors, together with their ...
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(2010-04-15)Department: PharmacologyMuscarinic acetylcholine receptors (mAChRs), specifically M1 and M4 subtypes, provide viable targets for the treatment of multiple central nervous system disorders. However, highly selective activators of either M1 or M4 ...