Browsing by Subject "association"

Now showing items 1-5 of 5

    • Genetic and phenotypic dissection of autism susceptibility 
      McCauley, Jacob Lee (2005-03-09)
      Department: Molecular Physiology and Biophysics
      Autism is a severe neurodevelopmental disorder characterized by deficits in language and social interaction, and patterns of repetitive and stereotyped behaviors, interests and activities. Evidence indicates that autism ...
    • Investigation of genetic susceptibility to late-onset Alzheimer disease through genomic convergence 
      Liang, Xueying (2007-04-16)
      Department: Human Genetics
      With the exception of ApoE gene, no universally accepted genetic association has been identified with the complex Late-onset Alzheimer Disease (LOAD). A broad region of chromosome 10 has engendered continued interest ...
    • Parkinson Disease Loci in the Mid-Western Amish 
      Davis, Mary Feller (2013-04-15)
      Department: Interdisciplinary Studies: Applied Statistics
      Previous evidence has shown that Parkinson disease (PD) has a heritable component, but only a small proportion of the total genetic contribution to PD has been identified. Genetic heterogeneity complicates the verification ...
    • Power and type 1 error for large pedigree analyses of binary traits 
      Cummings, Anna Christine (2012-12-07)
      Department: Interdisciplinary Studies: Applied Statistics
      Studying population isolates with large, complex pedigrees has many advantages for discovering genetic susceptibility loci; however, statistical analyses can be computationally challenging. Allelic association tests need ...
    • Towards an understanding of the role of chromosome 15q11-q13 in idiopathic autism 
      Delahanty, Ryan James (2010-01-29)
      Department: Human Genetics
      TOWARD AN UNDERSTANDING OF THE ROLE OF CHROMOSOME 15Q11-Q13 IN IDIOPATHIC AUTISM RYAN JAMES DELAHANTY Dissertation under the direction of Dr. James S. Sutcliffe The 15q11-q13 region is a genomic interval ...