Browsing by Subject "autoimmunity"
Now showing items 1-5 of 5
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(2006-10-09)Department: Microbiology and ImmunologySelf-reactive B lymphocytes are frequently produced as a consequence of B cell antigen receptor rearrangement. Autoreactive B cells that are not eliminated or inactivated by tolerance mechanisms survive and mature in the ...
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(2018-11-16)Department: Biomedical EngineeringT cell activity is dysregulated in a number of autoimmune diseases for which systemic lupus erythematosus is a prime example. Treatment options are limited and usually consist of overt immune suppression and compromised ...
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(International Journal of Nanomedicine, 2020)Background: Helper T cell activity is dysregulated in a number of diseases including those associated with rheumatic autoimmunity. Treatment options are limited and usually consist of systemic immune suppression, resulting ...
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(2014-10-01)Department: BiochemistryDuring development of the nervous system, approximately 50% of the neurons generated undergo apoptosis as part of a normal pruning process. The neuronal corpses must be efficiently cleared to prevent an immune system ...
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(2012-03-31)Department: PathologyPatients with the autoimmune disease systemic lupus erythematosus (SLE) have an increased risk of developing premature cardiovascular disease, most notably atherosclerosis. While the mechanisms behind this increased risk ...