Browsing by Subject "beta cells"

Now showing items 1-3 of 3

    • Examining the roles of MafB in the pancreatic islet 
      Conrad, Elizabeth Elrod (2015-10-20)
      Department: Molecular Physiology and Biophysics
      Analysis of MafB-/- mice suggested that this transcription factor was essential to islet α- and β-cell formation during development, although the postnatal physiological impact could not be studied because these mutants ...
    • Exploring the Function of G6PC2 in Pancreatic Islet Beta Cells 
      Boortz, Kayla Ann (2016-10-03)
      Department: Molecular Physiology and Biophysics
      MOLECULAR PHYSIOLOGY & BIOPHYSICS Exploring the Function of G6PC2 in Pancreatic Islet Beta Cells Kayla Boortz Dissertation under the direction of Professor Richard O’Brien, Ph.D. G6PC2 encodes an islet-specific ...
    • Variables that influence transcription factor-mediated acinar to beta cell reprogramming 
      Clayton, Hannah Worchel (2017-02-24)
      Department: Cell and Developmental Biology
      Reprogramming of pancreatic cells into new beta-like cells is a potential therapy for Type 1 diabetes. Pancreatic acinar cells are an appealing target for cellular reprogramming since they are abundant, derived from a ...