Browsing by Subject "beta-hematin"

Now showing items 1-3 of 3

    • Hemozoin: A Paradigm for Biomineralization in Disease 
      Carter, Melissa Diane (2009-07-19)
      Department: Chemistry
      Biomineralization is the formation of organic-inorganic composites by organisms. Originally evolved as a protective mechanism, this complex process has also become a recognized contributor to several disease states, ranging ...
    • Hemozoin: A Target-Based Approach to Antimalarial Drug Discovery 
      Sandlin, Rebecca Davis (2013-02-26)
      Department: Chemistry
      The emergence of drug resistant strains of Plasmodium spp. creates a critical need for the development of novel antimalarials. Hemozoin, a crystalline heme detoxification biomineral vital to parasite survival, serves as ...
    • The role of fatty acid oxidation in disruption of macrophage function 
      Rutledge, Alexandra Catherine (2009-04-10)
      Department: Chemistry
      Hemozoin (Hz), the heme detoxification biomineral formed during the intraerythrocytic stage of malaria, has long been suspected of contributing to immunomodulations that occur during P. falciparum infection. Rupture of ...