Browsing by Subject "biochemistry"

Now showing items 1-5 of 5

    • Investigations of Orthosomycin Biosynthesis 
      McCranie, Emilianne Karyl (2015-12-16)
      Department: Chemistry
      Orthosomycins are highly decorated oligosaccharides with potent activity against a variety of Gram-positive bacteria including methicillin-resistant staphylococci and vancomycin-resistant enterococci. The research in this ...
    • Molecular Genetic Dissection of the RNA Polymerase II Transcription Factor D (TFIID) Subunit Taf2 
      Feigerle, Jordan Taylor (2016-12-13)
      Department: Molecular Physiology and Biophysics
      The evolutionarily conserved 14-subunit RNA Polymerase II Transcription Factor D (TFIID) complex is composed of TATA-box Binding Protein (TBP) and 13 TBP-associated factors (Tafs). In Saccharomyces cerevisiae, TFIID is ...
    • Oxidative metabolism of exocyclic DNA adducts 
      Knutson, Charles Gerhard Francesco (2008-03-13)
      Department: Biochemistry
      Multiple exocyclic DNA adducts arise from reactions of lipid and DNA peroxidation products with DNA bases. These endogenous lesions are mutagenic; therefore, monitoring adduct levels may provide a means of assessing genomic ...
    • Proteomic Signatures of Epidermal Growth Factor Receptor Signaling 
      Myers, Matthew V (2012-01-25)
      Department: Biochemistry
      Analysis of cellular signaling networks typically involves targeted measurements of phosphorylated protein intermediates. However, phosphoproteomic analyses usually require affinity enrichment of phosphopeptides and ...
    • Signaling mechanisms associated with the platelet collagen receptors 
      Marjoram, Robin James (2011-02-25)
      Department: Pathology
      Cellular adhesions to the extracellular matrix (ECM) and to neighboring cells are vital interactions within metazoans. This dissertation examines cellular adhesion by utilizing the adhesive interaction between platelets ...