Browsing by Subject "biophysics"
Now showing items 1-6 of 6
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(2017-04-05)Department: PhysicsIn the series of morphogenetic events that are required for Drosophila development, some of the most dramatic are those that involve the coordinated movement of the germband and amnioserosa, two epithelia that remain ...
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(2018-09-20)Department: PhysicsThis work applies novel inverse modeling techniques to both chemical kinetics in lab-on-chip devices and cell mechanics in developing Drosophila embryos. The aim is to describe these systems quantitatively; to compare ...
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(2011-09-06)Department: BiochemistryBotulinum neurotoxin (BoNT) belongs to a large class of toxic proteins that act by enzymatically modifying cytosolic substrates within eukaryotic cells. The process by which a catalytic moiety is transferred across a ...
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(2016-07-29)Department: Chemical EngineeringEnzymatic proteins catalyze biochemical reactions central to many cellular processes. Across all kingdoms of life, members of the AAA+ (ATPases associated with diverse cellular activities plus) superfamily of enzymes convert ...
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Structural and Biophysical Investigation of Calmodulin Binding to the Third Domain of Human Prp40A (2022-06-15)Department: Chemical & Physical BiologyHuman Pre-mRNA-processing factor 40 homolog A (hPrp40A) is a splicing factor that interacts with the Huntington’s Disease (HD) protein huntingtin (HTT). Evidence has accumulated that both HTT and hPrp40A are modulated by ...
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(Vanderbilt University. Dept. of Physics and Astronomy, 2019-04-18)Given an image of an epithelial cell sheet, CellFIT can infer cellular forces by segmenting the image into individual cells, constructing equilibrium equations for the points where cells meet at triple junctions, and finding ...