Browsing by Subject "blood-brain barrier"

Now showing items 1-4 of 4

    • Characterization of the metabolic properties of brain microvascular endothelial cells 
      Marinelli, Nicholas Anthony (2019-07-24)
      Department: Chemical and Physical Biology
      The blood-brain barrier (BBB) is a highly restrictive and regulated vascular network, strictly controlling the molecules that enter the brain via the bloodstream, while also serving an important role in the removal of toxic ...
    • Electrochemical Instrumentation for Real-Time Monitoring of Biological Model Systems 
      Cognata, Andrew David (2016-04-11)
      Department: Chemistry
      New technologies for model biological systems aid in drug development and toxicology by providing an in vitro environment that closely mimics in vivo conditions but require new instrumentation to meet needs in monitoring ...
    • Targeted Interrogation of Blood-Brain Barrier Biology 
      Neal, Emma Hollmann; 0000-0003-0595-9694 (2020-03-11)
      Department: Chemical Engineering
      The blood-brain barrier (BBB) is formed by endothelial cells that line brain vasculature and separate the blood stream and central nervous system parenchyma. The BBB functions as an exceptionally dynamic molecular gatekeeper, ...
    • TREM2 Associations with Concomitant Pathology in Alzheimer’s Disease 
      Winfree, Rebecca Lynn; 0000-0001-9798-2589 (2022-08-17)
      Department: Pharmacology
      Differential expression of both Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) and its soluble fragment have been linked to Alzheimer’s disease (AD) risk in animal models and humans. The TREM2 pathway represents ...