Browsing by Subject "carcinogens"

Now showing items 1-2 of 2

    • DNA-Protein Cross-Links Induced by Bis-Electrophiles 
      Loecken, Elisabeth Mary (2010-04-30)
      Department: Biochemistry
      Diepoxybutane is a mutagenic and carcinogenic oxidation product of the important industrial chemical and environmental contaminant butadiene. The mutagenic potential of diepoxybutane is thought to be due in part to its ...
    • Formation, Degradation, and Bypass of DNA-Protein Crosslinks 
      Sedgeman, Carl Andrew (2018-09-18)
      Department: Biochemistry
      The preservation of DNA replication is requisite for cellular integrity and prevention of tumor formation and cell death. The Y-family DNA polymerases (Pol eta, kappa, iota, and REV1) are crucial in this process because ...