Browsing by Subject "cataract"
Now showing items 1-3 of 3
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(2008-01-17)Department: Molecular Physiology and BiophysicsSmall heat shock proteins (sHSPs) are a ubiquitous family of chaperones that protect unfolded proteins from irreversible aggregation in the cell. Human sHSPs are associated with the pathology of a variety of diseases. The ...
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(Cells, 2023-01-13)Age-related protein truncation is a common process in long-lived proteins such as proteins found in the ocular lens. Major truncation products have been reported for soluble and membrane proteins of the lens, including ...
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(2018-07-16)Department: Chemical and Physical BiologyαB-crystallin is a member of the small heat shock protein (sHSP) superfamily. Mutations in αB-crystallin cause autosomal cataracts and cardiomyopathy, but the exact role of αB-crystallin in the lens and heart remains ...