Browsing by Subject "catenin"
Now showing items 1-2 of 2
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(2015-12-09)Department: Cancer BiologyIn vertebrate epithelia, p120-catenin mediates E-cadherin stability and suppression of RhoA. Genetic ablation of p120 in various epithelial tissues typically causes striking alterations in tissue function and morphology. ...
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(2012-04-04)Department: Cancer BiologyCadherins and catenins are important regulators of tissue homeostasis and cancer. Here, we report critical roles for p120 catenin (p120) in mammary development and breast cancer. In the untransformed gland, p120 ablation ...