Browsing by Subject "click chemistry"
Now showing items 1-4 of 4
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(2018-11-15)Department: Biomedical EngineeringAdvanced organic chemistry allows for design of unique nanocarriers that have specific functions tailored for in vivo applications, such as decorating with mannose to target tumor-associated macrophages for immunotherapy ...
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(2016-07-29)Department: Chemical and Physical BiologyMetals, such as iron, zinc, and manganese, are required for bacterial function and survival. Bacteria have evolved systems to acquire metals from the environments they inhabit. Pathogenic bacteria must obtain metals from ...
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(2016-11-17)Department: BiochemistryOxidative stress is a contributing factor in a number of chronic diseases, including cancer, atherosclerosis, and neurodegenerative diseases. Lipid peroxidation that occurs during periods of oxidative stress and decomposition ...
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(2015-07-21)Department: ChemistryPolyunsaturated Fatty Acids (PUFAs) are oxidized both enzymatically and by autoxidation to many inflammatory signaling molecules, which have been detected in multiple disease states. Oxidized PUFAs can further react to ...