Browsing by Subject "computational structural biology"
Now showing items 1-2 of 2
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(2013-07-29)Department: Chemical and Physical BiologyThe metabotropic glutamate receptor subtype 5 (mGlu5), a class C G-protein coupled receptor (GPCR), is involved in cognitive function through diverse signaling pathways that modulate synaptic plasticity. Modulators of mGlu5 ...
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(2014-06-26)Department: Biomedical InformaticsDe novo protein structure prediction is a challenge due to the sheer size of the search space. One can limit the set of potential models with long-range contact restraints (positions distant in the primary sequence but ...