Browsing by Subject "controlled release"
Now showing items 1-4 of 4
-
(International Journal of Nanomedicine, 2020)Background: Helper T cell activity is dysregulated in a number of diseases including those associated with rheumatic autoimmunity. Treatment options are limited and usually consist of systemic immune suppression, resulting ...
-
(2010-06-07)Department: ChemistryWhile traditional polyesters, such as poly(lactic acid) and poly(glycolic acid), have long been of interest for the development of nanoparticles as effective drug delivery devices, they are restricted in their utility due ...
-
Polyurethane scaffold with delivery of biologically active small molecules for tissue regeneration (2010-04-27)Department: Chemical EngineeringLimited availability of autograft tissue for bone and skin wound healing has established the demand for improved synthetic biomaterials. Biodegradable polyurethane (PUR) scaffolds exhibit favorable properties for wound ...
-
(2011-10-27)Department: Biomedical EngineeringControlled gene silencing technologies have significant, unrealized potential for use in tissue regeneration applications. The design described herein provides a means to package and protect siRNA within pH-responsive, ...