Browsing by Subject "dopamine transporter"
Now showing items 1-7 of 7
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(2012-12-11)Department: Molecular Physiology and BiophysicsInsulin secretion is the natural response to hyperglycemia, and it is crucial to maintain glucose homeostasis in healthy individuals. Impairment in this regulation eventually results in Type-2 diabetes. From the perspective ...
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Modeling Molecular And Physiological Contributions To Dopamine-Associated Neuropsychiatric Disorders (2018-06-07)Department: NeuroscienceGenetic and imaging studies implicate disrupted DA availability in multiple psychiatric disorders, yet how variation in DA-linked genes leads to disease is unclear. Dopamine (DA) neurotransmission is controlled by the D2 ...
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(2012-12-14)Department: NeuroscienceA myriad of human behaviors, such as mood, awareness and motivation, are modulated by the monoamine neurotransmitters serotonin, norepinephrine and dopamine, respectively. Consequently, dysfunction of these monoaminergic ...
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(2018-04-04)Department: Biological SciencesThe initial steps of vision - the transduction and encoding of physical light stimuli into neural signals - occur in the retina, a multi-layered sheet of neurons that lines the back of the eye. Retinal dopamine (DA) acts ...
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(2017-11-28)Department: NeuroscienceOur lab has created a construct valid mouse model based on the dopamine transporter (DAT) Val559 coding variant to elucidate neurobiological mechanisms supporting ADHD and other dopamine (DA)-linked comorbid disorders. ...
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(2013-12-03)Department: ChemistryThe presynaptic, cocaine- and amphetamine-sensitive dopamine (DA) transporter (DAT, SLC6A3) controls the intensity and duration of synaptic dopamine signals by rapid clearance of the neurotransmitter back into presynaptic ...
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(2017-02-22)Department: PharmacologyThe dopamine (DA) transporter (DAT) is a presynaptic membrane protein that regulates dopaminergic neurotransmission by controlling DA levels at the synapse via active reuptake. The DAT is also capable of engaging in reverse ...