Browsing by Subject "epilepsy"
Now showing items 1-9 of 9
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(2012-12-07)Department: NeuroscienceThe proper function of the nervous system is dependent upon a delicate balance between excitatory and inhibitory activity in the brain. GABAA receptors are extremely important in the maintenance of this balance because ...
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(2021-03-30)Department: Electrical EngineeringThe analysis of image data in image guided surgery can produce promising insights to improve patient outcomes, since medical images provide detailed, patient-specific data on how an intervention affects the anatomy – or ...
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(2008-07-17)Department: PharmacologyInvestigating genetic forms of epilepsy allows for improved understanding of epilepsy pathophysiology in general. Mutations in voltage-gated sodium channels are a frequent cause of genetic forms of epilepsy. First we ...
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(2023-03-27)Department: NeuroscienceEpilepsy is one of the most common neurological disorders, and current treatments fail to provide seizure control for ~30% of patients. Most pharmacological treatments target ion channels and neurotransmission, yet the ...
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(2013-07-18)Department: NeuroscienceGABAA receptors are pentameric, ligand-gated chloride channels that mediate the majority of fast inhibition in the brain. Because they are assembled from an array of 19 subunit subtypes, GABAA receptors are remarkable ...
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(2012-05-25)Department: PharmacologyMutations in inhibitory GABAA receptor γ2 subunit gene, GABRG2, have been associated with genetic epilepsy syndromes including childhood absence epilepsy (CAE), pure febrile seizures (FS), generalized epilepsy with febrile ...
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(2014-10-29)Department: NeuroscienceEpilepsy is a common neurological disease characterized by an enduring predisposition to generate seizures. Although multiple factors contribute to epilepsy, the majority of cases are genetic in origin. Variable expressivity ...
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(2014-03-18)Department: PharmacologyPHARMACOLOGY Pharmacological and Genetic Rescue of Idiopathic Epilepsies Lyndsey Leigh Anderson Dissertation under the direction of Professor Alfred George, Jr. Epilepsy is a common neurological disorder affecting ...
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(Frontiers in Neuroscience, 2019-09-12)The annual deep brain stimulation (DBS) Think Tank aims to create an opportunity for a multidisciplinary discussion in the field of neuromodulation to examine developments, opportunities and challenges in the field. The ...