Browsing by Subject "factor IX"

Now showing items 1-2 of 2

    • A mechanism for exosite-mediated factor IX activation by factor XIa 
      Geng, Yipeng (2014-04-19)
      Department: Pathology
      Factor XI (FXI) is the zymogen of a protease (FXIa) that contributes to blood coagulation by activating factor IX (FIX). This thesis presents several novel observations regarding the structure and function of FXI that will ...
    • The molecular mechanism of factor IX activation by factor XIa 
      Smith, Stephen Bradford (2009-04-09)
      Department: Pathology
      Activation of coagulation factor IX is a pivotal reaction in the formation and maintenance of a fibrin clot. Factor IX is activated by two structurally unrelated enzymes; factor XIa of the intrinsic coagulation cascade and ...