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Mean Coronary Cross-Sectional Area as a Measure of Arterial Remodeling Using Noncontrast CT Imaging in Persons With HIV
(Journal Of The American Heart Association, 2022-12-06)
BackgroundPersons with HIV have a higher prevalence of coronary artery disease compared with their HIV-negative counterparts. Earlier identification of subclinical atherosclerosis may provide a greater opportunity for ...
Occupational demands associated with rotator cuff disease surgery in the UK Biobank
(Scand J Work Environ Health, 2022-10)
Objectives Physically-demanding occupations may increase rotator cuff disease (RCD) risk and need for sur- gery. We linked a job-exposure matrix (JEM) to the UK Biobank cohort study to measure physical occupational exposures ...
Benign Neurofibroma/Schwannoma Hybrid Peripheral Nerve Sheath Tumor of the Ulnar Nerve Harboring a Metastatic Papillary Thyroid Carcinoma Deposit: A Case Report of Tumor-to-Tumor Metastasis
(Case Reports In Pathology, 2022-12-14)
A 74-year-old man with a medical history significant for papillary thyroid cancer (PTC) presented with a rapidly enlarging grape-sized mass in his right medial arm with paresthesia in the ulnar nerve distribution. Imaging ...
Post-COVID-19 human memory impairment: A PRISMA-based systematic review of evidence from brain imaging studies
(Frontiers In Aging Neuroscience, 2022-12-09)
Many people with coronavirus disease 2019 (COVID-19) report varying degrees of memory impairment. Neuroimaging techniques such as MRI and PET have been utilized to shed light on how COVID-19 affects brain function in humans, ...
Reforming Reimbursement for the US Food and Drug Administration's Accelerated Approval Program to Support State Medicaid Programs
(Jama Health Forum, 2022-11-18)
IMPORTANCE The US Food and Drug Administration (FDA) has an accelerated approval program that has become the subject of scholarly attention and criticism, not only for the FDA's oversight of the program but also for its ...
Analysis of apoB Concentrations Across Early Adulthood and Predictors for Rates of Change Using CARDIA Study Data
(Journal of Lipid Research, 2022-12)
The cumulative exposure to apolipoprotein B (apoB)-containing lipoproteins in the blood during early adult life is a central determinant of atherosclerotic cardiovascular disease risk. To date, the patterns and rates of ...
Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma A Phase 3 Prospective Externally Controlled Cohort Trial
(JAMA Oncology, 2022-11-17)
IMPORTANCE Glioblastoma is the most lethal primary brain cancer. Clinical outcomes for glioblastoma remain poor, and new treatments are needed.
OBJECTIVE To investigate whether adding autologous tumor lysate-loaded ...
The nutraceutical electrophile scavenger 2-hydroxybenzylamine (2-HOBA) attenuates gastric cancer development caused by Helicobacter pylori
(Biomedicine & Pharmacotherapy, 2022-12-06)
Stomach cancer is a leading cause of cancer death. Helicobacter pylori is a bacterial gastric pathogen that is the primary risk factor for carcinogenesis, associated with its induction of inflammation and DNA damage. ...
Neutralization fingerprinting technology for characterizing polyclonal antibody responses to dengue vaccines
(Cell Reports, 2022-12-13)
Dengue is a major public health threat. There are four dengue virus (DENV) serotypes; therefore, efforts are focused on developing safe and effective tetravalent DENV vaccines. While neutralizing antibodies contribute to ...
Service delivery challenges in HIV care during the first year of the COVID-19 pandemic: results from a site assessment survey across the global IeDEA consortium
(Journal Of The International Aids Society, 2022-12-11)
IntroductionInterruptions in treatment pose risks for people with HIV (PWH) and threaten progress in ending the HIV epidemic; however, the COVID-19 pandemic's impact on HIV service delivery across diverse settings is not ...