RSS 1.0Department of Pharmacology
Our research interests include five major areas: signal transduction neuroscience bioactive lipid metabolism genetic basis of cardiovascular dysfunction drug metabolism
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Recent Submissions
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(International Journal Of Molecular Sciences, 2022-12-26)Scientists have long established that fatty acids are the primary substrates for kidney mitochondria. However, to date we still do not know how long-chain and middle-chain fatty acids are oxidized at the mitochondrial ...
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(Blood Pressure, 2023-01-03)
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(Metabolites, 2022-11-29)This study aimed to evaluate whether the single nucleotide polymorphisms of ATP-binding cassette subfamily G member 2 (ABCG2) and solute carrier family 2 member 9 (SLC2A9) affect individual blood uric acid levels using ...
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(Metabolites, 2022-11-29)This study aimed to evaluate whether the single nucleotide polymorphisms of ATP-binding cassette subfamily G member 2 (ABCG2) and solute carrier family 2 member 9 (SLC2A9) affect individual blood uric acid levels using ...
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(International Journal of Nanomedicine, 2020)Background: Helper T cell activity is dysregulated in a number of diseases including those associated with rheumatic autoimmunity. Treatment options are limited and usually consist of systemic immune suppression, resulting ...
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(BMC Pharmacology & Toxicology, 2020-01-06)Background 2-Hydroxybenzylamine (2-HOBA) is a selective dicarbonyl electrophile scavenger being developed as a nutritional supplement to help protect against the development of conditions associated with dicarbonyl ...
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(British Journal of Pharmacology, 2019-06)Background and Purpose Emerging evidence indicates that hypertension is mediated by immune mechanisms. We hypothesized that exposure to Porphyromonas gingivalis antigens, commonly encountered in periodontal disease, can ...
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(American Journal of Health-System Pharmacy, 2020-01-15)Purpose High-quality medication reconciliation reduces medication discrepancies, but smaller hospitals serving rural patients may have difficulty implementing this because of limited resources. We sought to adapt and ...
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(Advances in Therapy, 2019-09)Introduction As continuous exposure to anticholinergics has been associated with adverse outcomes, accurately measuring exposure is important. However, no gold standard measure is available, and the performance of existing ...
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(Journal of Pharmacology and Experimental Therapeutics, 2019-06-01)Active transport by renal proximal tubules plays a significant role in drug disposition. During drug development, estimates of renal excretion are essential to dose determination. Kidney bioreactors that reproduce physiologic ...
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(INTENSIVE CARE MEDICINE, 2019-07)ObjectiveTo identify the key mechanisms that clinicians perceive improve care in the intensive care unit (ICU), as a result of their involvement in post-ICU programs.MethodsQualitative inquiry via focus groups and interviews ...