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Blunted Social Reward Responsiveness Moderates the Effect of Lifetime Social Stress Exposure on Depressive Symptoms
(Frontiers in Behavioral Neuroscience, 2019-08-07)
Exposure to social stress is a well-established risk factor for the development and recurrence of depression. Reduced neural responsiveness to monetary reward has been associated with greater symptoms following stress ...
Proceedings of the Sixth Deep Brain Stimulation Think Tank Modulation of Brain Networks and Application of Advanced Neuroimaging, Neurophysiology, and Optogenetics
(Frontiers in Neuroscience, 2019-09-12)
The annual deep brain stimulation (DBS) Think Tank aims to create an opportunity for a multidisciplinary discussion in the field of neuromodulation to examine developments, opportunities and challenges in the field. The ...
Double-blind, randomized, placebo-controlled study of trofinetide in pediatric Rett syndrome
(Neurology, 2019-04-16)
Objective
To determine safety, tolerability, and pharmacokinetics of trofinetide and evaluate its efficacy in female children/adolescents with Rett syndrome (RTT), a debilitating neurodevelopmental condition for which ...
Spatiotemporal trajectories of quantitative magnetization transfer measurements in injured spinal cord using simplified acquisitions
(Neuroimage-/Clinical, 2019)
Abstract
Purpose: This study aims to systematically evaluate the accuracy and precision of pool size ratio (PSR) measurements from quantitative magnetization transfer (qMT) acquisitions using simplified models in the ...
A novel system for introducing precisely-controlled, unanticipated gait perturbations for the study of stumble recovery
(Journal of Neuroengineering and Rehabiliation, 2019-06-20)
BackgroundThe experimental study of stumble recovery is essential to better understanding the reflexive mechanisms that help prevent falls as well as the deficiencies in fall-prone populations. This study would benefit ...
Deletion of Semaphorin 3F in Interneurons Is Associated with Decreased GABAergic Neurons, Autism-like Behavior, and Increased Oxidative Stress Cascades
(Molecular Neurobiology, 2019-08)
Autism and epilepsy are diseases which have complex genetic inheritance. Genome-wide association and other genetic studies have implicated at least 500+ genes associated with the occurrence of autism spectrum disorders ...
Pediatric Prolonged-Release Melatonin for Sleep in Children with Autism Spectrum Disorder: Impact on Child Behavior and Caregiver's Quality of Life
(Journal of Autism and Developmental Disorders, 2019-08)
A randomized, 13-weeks, placebo-controlled double-blind study in 125 subjects aged 2-17.5years with Autism Spectrum Disorder or Smith-Magenis syndrome and insomnia demonstrated efficacy and safety of easily-swallowed ...
Insights From Dynamic Neuro-Immune Imaging on Murine Immune Responses to CNS Damage
(Frontiers in Neuroscience, 2019-07-17)
Evolving technologies and increasing understanding of human physiology over the past century have afforded our ability to intervene on human diseases using implantable biomaterials. These bio-electronic devices present a ...
Graphene-Based Nanomaterials: From Production to Integration With Modern Tools in Neuroscience
(2019-07-16)
Graphene, a two-dimensional carbon crystal, has emerged as a promising material for sensing and modulating neuronal activity in vitro and in vivo. In this review, we provide a primer for how manufacturing processes to ...
Procedural Memory Following Moderate-Severe Traumatic Brain Injury: Group Performance and Individual Differences on the Rotary Pursuit Task
(Frontiers in Human Neuroscience, 2019-07-19)
The impact of traumatic brain injury (TBI) on procedural memory has received significantly less attention than declarative memory. Although to date studies on procedural memory have yielded mixed findings, many rehabilitation ...