Browsing by Department "Biological Sciences"
Now showing items 41-60 of 157
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(2014-03-04)Department: Biological SciencesIn the sixth mass extinction, amphibians are being lost in greater numbers than almost any other taxon. The deadly skin disease, chytridiomycosis, has taken a great toll on amphibian populations around the globe. ...
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(2014-09-26)Department: Biological SciencesWolbachia pipientis is an obligate intracellular bacterium of increasing importance in understanding the tripartite interactions between viruses, bacteria, and eukaryotes, as well as having applications in modern medicine ...
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(2019-09-25)Department: Biological SciencesSong is a key aspect of oscine songbird behavior. Males that do not sing a species-typical song are unlikely to attract mates. Interestingly, young songbirds must listen to other conspecific males to learn an appropriate ...
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(2012-12-11)Department: Biological SciencesPhosphorylation of the C-terminus of cAR1 is thought to provide a role in the ability of cells to adapt to cAMP and respond to spatial gradients that span several orders of magnitude. It has been demonstrated that ...
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(2024-01-03)Department: Biological SciencesGlobally, severe fungal infections in humans cause serious disease and kill millions of people annually, but fungal infections remain understudied and poorly understood. The genus Aspergillus includes several hundred species ...
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(2011-08-04)Department: Biological SciencesThe work presented in this dissertation focuses on a how the telomerase complex assembles both in vivo and in vitro and begins to explore how one member of the telomerase enzyme in the budding yeast, Saccharomyces cerevisiae, ...
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(2013-04-15)Department: Biological SciencesThe work presented in this dissertation focuses on the temporal regulation of telomerase complex assembly in the yeast Saccharomyces cerevisiae as mediated by protein degradation of a core subunit during G1 phase of the ...
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(2012-09-27)Department: Biological SciencesTraversal of the hemocoel, avoiding or surviving interactions with the insect’s innate immune system, invasion of the female mosquito’s salivary glands, and injection into the vertebrate host, are necessary steps for disease ...
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(2013-02-21)Department: Biological SciencesInsects are able to detect a wide range of volatiles through a family of cell-surface odorant receptors (ORs), which are activated by specific odorants and relay the signal to the brain. Insect ORs function as heteromultimeric ...
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(2021-03-25)Department: Biological SciencesExtracellular vesicles (EVs) are mediators of cell-cell communication and play important roles in many physiological processes including cancer and drug resistance. EVs are nanosized particles secreted from every cell, ...
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(2020-07-13)Department: Biological SciencesRetina regeneration has been proposed as a potential treatment for retinal diseases. Unlike mammals, zebrafish are capable of naturally regenerating the retina in response to damage. This has led to a concerted effort to ...
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(2013-07-29)Department: Biological SciencesDissertation under the direction of Professor Bruce H. Appel Oligodendrocytes are specialized glial cells in the vertebrate central nervous system (CNS) that extend processes to wrap axons in myelin sheaths. Their number ...
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(2013-03-29)Department: Biological SciencesParapineal precursors arise from the medially located pineal complex anlage and migrate to the left side of the brain. Published data implicates Fgf8a in the migration of parapineal cells away from the midline of the pineal ...
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(2014-09-24)Department: Biological SciencesCircadian clocks are the endogenous timing mechanisms that facilitate organisms to adapt to the daily cycles on the earth. Previous studies have demonstrated that cyanobacterial circadian clock enhances fitness under cyclic ...
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(2024-02-13)Department: Biological SciencesMetabolic syndrome, cardiovascular disease, and infertility are pressing global health concerns that necessitate an in-depth exploration of their genetic underpinnings. One such genetic determinant is ATP10A, a flippase ...
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(2013-11-18)Department: Biological SciencesThis dissertation is concerned with the expression patterns, functionality and mechanisms of disease vector mosquito odorant receptors. The principal afrotropical vector for malaria, Anopheles gambiae, discriminates human ...
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(2008-04-04)Department: Biological SciencesHuman replication protein A (RPA) is a single-stranded DNA (ssDNA) binding protein involved in DNA metabolism. RPA binds ssDNA transiently during initiation of DNA replication. When this dissertation research began, the ...
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(2013-07-29)Department: Biological SciencesThe social amoeba Dictyostelium discoideum senses the bacterial metabolite folic acid to track down bacteria. Previous studies suggested that the folic acid receptor is a serpentine receptor. In this study, I examined the ...
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(2022-03-29)Department: Biological SciencesDeep genome sequencing of the fungal kingdom, an ancient and diverse eukaryotic lineage, has shed light on the dynamics of genome evolution. For example, these studies have underscored the importance of evolution by gene ...
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(2018-10-19)Department: Biological SciencesRecent advances in sequencing technology have greatly decreased the cost and increased the availability of genomic data. Armed with this rich base of information, it has become feasible to pursue the study of complex ...