Browsing by Title
Now showing items 2398-2417 of 17440
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(2015-03-27)Department: Cell and Developmental BiologyThe intestinal epithelium is a continuously renewing tissue. This rapid renewal is fueled by stem cells that reside in the base of the crypts of Lieberkühn, the functional unit of the intestinal epithelium. The identity ...
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(2014-03-31)Department: Chemical EngineeringProduction of high-purity oxygen from air by pressure-swing adsorption (PSA) is of interest for a variety of applications. One recognized area for which this technology could be particularly useful is the development of ...
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(Vanderbilt University. Writing Studio, 2009-03-22)
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(2008-07-17)Department: PharmacologyInvestigating genetic forms of epilepsy allows for improved understanding of epilepsy pathophysiology in general. Mutations in voltage-gated sodium channels are a frequent cause of genetic forms of epilepsy. First we ...
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(2014-12-22)Department: ChemistryThe work presented here is the first of its kind where nanocrystal-based photovoltaics are characterized by directly imaging the electronic properties and correlating them to the structure of the sample. Through electron ...
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(2018-08-31)Department: Molecular Physiology and BiophysicsStress is a precipitating agent in neuropsychiatric disease and initiates relapse to drug-seeking behavior in addicted patients. Targeting the stress system in protracted abstinence from drugs of abuse with anxiolytics may ...
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(2010-08-04)Department: Biological SciencesA systematic Drosophila forward genetic screen for photoreceptor synaptic transmission mutants identified no-on-and-no-off transient C (nonC) based on loss of retinal synaptic responses to light stimulation. The cloned ...
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(2021-12-06)Department: Electrical EngineeringDevice-level radiation-induced photocurrent measurements, for characterization purposes and use in radiation hardening by design (RHBD) techniques, have historically been performed through off-chip measurements of ...
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(2011-08-01)Department: ChemistryCharacterization of Post-Translationally Modified Peptides and Proteins Using Lanthanide-Based Labeling Strategies By Randi Gant-Branum Abstract: Numerous biological processes are regulated by the stoichiometry of protein ...
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(2023-03-24)Department: Electrical EngineeringThis research presents a methodology for on-chip measurement of transient photocurrent for technology characterization and mechanism discovery with implementation and demonstration in two sub-50nm silicon-on-insulator (SOI) ...
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(2008-07-27)Department: Biomedical EngineeringRaman spectroscopy has the potential for providing differential diagnosis between dysplasia and benign cervix with high sensitivity and specificity. Two in vivo studies where designed to further evaluate the potential and ...
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Characterization of Recent Evolutionary Signatures of Genetic Elements involved in Human Pregnancy (2019-05-08)Department: Biological SciencesEutherian pregnancy is characterized by relatively prolonged gestation and early establishment of direct maternal-fetal contact. In order to support extended growth of a genetically distinct fetus, the maternal immune ...
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(2013-12-02)Department: Earth and Environmental SciencesThis project attempts to identify the source of surface water and groundwater salinity observed in a polder in southwest Bangladesh through geochemical analyses. All surface water samples are mixtures of tidal channel ...
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(2014-07-28)Department: Electrical EngineeringThe response of electronic devices to ionizing radiation is a reliability concern for commercial and space applications. An ionizing particle can cause charge to be generated and collected at the node of a circuit. If the ...
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(2009-04-21)Department: Electrical EngineeringAs technology nodes scale smaller, digital circuits are able to run at higher clock frequencies, but they can become more susceptible to single-event induced errors. These types of errors can be generated in combinational ...
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Characterization of SRAP Domain DNA-Protein Crosslink Formation and Reversal with DNA Abasic Sites (2022-06-27)Department: BiochemistryApuirinic/apyrimidinic (AP, or abasic) sites in DNA are one of the most common forms of DNA damage. AP sites are reactive and form crosslinks to both proteins and DNA, are prone to strand breakage, and inhibit DNA replication ...
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(2005-04-06)Department: Cell and Developmental BiologyHypoxia inducible vascular endothelial growth factor (VEGF) plays a major role in initiation and regulation of retinal neovascularization, which is the leading cause of severe vision loss and irreversible blindness in ...
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(2014-08-15)Department: PathologyThe oncogenes Mdm2 and Mdmx are often overexpressed in many human cancers. In addition to being negative regulators of the tumor suppressor p53, there is evidence these proteins have important p53-independent functions ...
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(2018-11-27)Department: ChemistryAlkylating agents, once a weapon of war employed in World War I, are the oldest class of chemotherapeutic agents still used today, with applications in treating a wide array of cancers. Methylating agents, in particular, ...
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(2023-07-21)Department: Biomedical EngineeringTumor-induced bone disease (TIBD) is associated with severe morbidities and reduced survival rates in metastatic cancer patients. Gli2 transcription factor plays a critical role in bone metastasis and TIBD by promoting ...