Browsing by Title
Now showing items 2418-2437 of 17687
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(2012-04-26)Department: PharmacologyProteostasis is maintained by a complex network of genes and processes which includes core synthesis and degradation machineries as well as chemical and protein chaperones. Much of what is known about the function and ...
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(2023-08-15)Department: NeuroscienceThe insular cortex (IC) integrates sensory and interoceptive cues to inform downstream circuitry executing adaptive behavioral responses. The IC communicates with areas involved canonically in stress and motivation. IC ...
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(2011-09-01)Department: Molecular Physiology and BiophysicsRecent genome wide association (GWA) studies have linked single nucleotide polymorphisms (SNPs) in the G6PC2 gene with elevated fasting plasma glucose (FPG) and in the SLC30A8 gene with altered susceptibility to type 2 ...
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(2015-03-27)Department: Cell and Developmental BiologyThe intestinal epithelium is a continuously renewing tissue. This rapid renewal is fueled by stem cells that reside in the base of the crypts of Lieberkühn, the functional unit of the intestinal epithelium. The identity ...
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(2014-03-31)Department: Chemical EngineeringProduction of high-purity oxygen from air by pressure-swing adsorption (PSA) is of interest for a variety of applications. One recognized area for which this technology could be particularly useful is the development of ...
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(Vanderbilt University. Writing Studio, 2009-03-22)
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(2008-07-17)Department: PharmacologyInvestigating genetic forms of epilepsy allows for improved understanding of epilepsy pathophysiology in general. Mutations in voltage-gated sodium channels are a frequent cause of genetic forms of epilepsy. First we ...
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(2014-12-22)Department: ChemistryThe work presented here is the first of its kind where nanocrystal-based photovoltaics are characterized by directly imaging the electronic properties and correlating them to the structure of the sample. Through electron ...
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(2024-03-12)Department: Data ScienceSeveral species in the genus Aspergillus can cause invasive aspergillosis (IA) in humans, an infectious disease that is often fatal in immunocompromised individuals. With a morbidity rate of >400,000 cases per year, the ...
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(2018-08-31)Department: Molecular Physiology and BiophysicsStress is a precipitating agent in neuropsychiatric disease and initiates relapse to drug-seeking behavior in addicted patients. Targeting the stress system in protracted abstinence from drugs of abuse with anxiolytics may ...
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(2010-08-04)Department: Biological SciencesA systematic Drosophila forward genetic screen for photoreceptor synaptic transmission mutants identified no-on-and-no-off transient C (nonC) based on loss of retinal synaptic responses to light stimulation. The cloned ...
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(2021-12-06)Department: Electrical EngineeringDevice-level radiation-induced photocurrent measurements, for characterization purposes and use in radiation hardening by design (RHBD) techniques, have historically been performed through off-chip measurements of ...
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(2011-08-01)Department: ChemistryCharacterization of Post-Translationally Modified Peptides and Proteins Using Lanthanide-Based Labeling Strategies By Randi Gant-Branum Abstract: Numerous biological processes are regulated by the stoichiometry of protein ...
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(2023-03-24)Department: Electrical EngineeringThis research presents a methodology for on-chip measurement of transient photocurrent for technology characterization and mechanism discovery with implementation and demonstration in two sub-50nm silicon-on-insulator (SOI) ...
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(2008-07-27)Department: Biomedical EngineeringRaman spectroscopy has the potential for providing differential diagnosis between dysplasia and benign cervix with high sensitivity and specificity. Two in vivo studies where designed to further evaluate the potential and ...
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Characterization of Recent Evolutionary Signatures of Genetic Elements involved in Human Pregnancy (2019-05-08)Department: Biological SciencesEutherian pregnancy is characterized by relatively prolonged gestation and early establishment of direct maternal-fetal contact. In order to support extended growth of a genetically distinct fetus, the maternal immune ...
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(2013-12-02)Department: Earth and Environmental SciencesThis project attempts to identify the source of surface water and groundwater salinity observed in a polder in southwest Bangladesh through geochemical analyses. All surface water samples are mixtures of tidal channel ...
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(2014-07-28)Department: Electrical EngineeringThe response of electronic devices to ionizing radiation is a reliability concern for commercial and space applications. An ionizing particle can cause charge to be generated and collected at the node of a circuit. If the ...
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(2009-04-21)Department: Electrical EngineeringAs technology nodes scale smaller, digital circuits are able to run at higher clock frequencies, but they can become more susceptible to single-event induced errors. These types of errors can be generated in combinational ...
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Characterization of SRAP Domain DNA-Protein Crosslink Formation and Reversal with DNA Abasic Sites (2022-06-27)Department: BiochemistryApuirinic/apyrimidinic (AP, or abasic) sites in DNA are one of the most common forms of DNA damage. AP sites are reactive and form crosslinks to both proteins and DNA, are prone to strand breakage, and inhibit DNA replication ...