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(2023-01-04)The study of circadian rhythms in bacteria was transformed by studies of the cyanobacterium Synechococcus elongatus. However, in a number of respects S. elongatus is atypical, and while those unusual characteristics were ...
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(Genome Research, 2022-10)There is increasing appreciation that, in addition to being shaped by an individual's genotype and environment, most complex traits are also determined by poorly understood interactions between these two factors. So-called ...
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(Ebiomedicine, 2022-12)Background Brugada syndrome (BrS) is a severe inherited arrhythmia syndrome that can be unmasked by fever.Methods A multicentre clinical analysis was performed in 261 patients diagnosed with fever-induced BrS, including ...
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(Diabetes, 2022-07)Mitochondrial glucose metabolism is essential for stimulated insulin release from pancreatic beta-cells. Whether mitofusin gene expression, and hence, mitochondrial network integrity, is important for glucose or incretin ...
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(Viruses-basel, 2022-12-15)The blood brain barrier (BBB) is a multicellular microenvironment that plays an important role in regulating bidirectional transport to and from the central nervous system (CNS). Infections by many acutely infectious viruses ...
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(Insects, 2022-11-28)Simple Summary Mosquitoes transmit disease, and over the past century, mosquito control has mostly relied on chemical insecticides that target the adult life stage. We review methods of mosquito control and argue that ...
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(Wiley, 2021-12-11)We studied if clinicians could gain sufficient working knowledge of a computer-assisted diagnostic decision support system (DDSS) (SimulConsult), to make differential diagnoses (DDx) of genetic disorders. We hypothesized ...
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(BMC Bioinformatics, 2019-12-04)Background: Advances in next-generation sequencing (NGS) of antibody repertoires have led to an explosion in B cell receptor sequence data from donors with many different disease states. These data have the potential to ...
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(Frontiers in Integrative Neuroscience, 2019-07-16)The remarkable physiology of the electric eel (Electrophorus electricus) made it one of the first model species in science. It was pivotal for understanding animal electricity in the 1700s, was investigated by Humboldt and ...
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(NATURE COMMUNICATIONS, 2019-07-12)Wolbachia is a genus of obligate intracellular bacteria found in nematodes and arthropods worldwide, including insect vectors that transmit dengue, West Nile, and Zika viruses. Wolbachia's unique ability to alter host ...
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(eLife, 2019-07-08)Iron storage proteins are essential for cellular iron homeostasis and redox balance. Ferritin proteins are the major storage units for bioavailable forms of iron. Some organisms lack ferritins, and it is not known how they ...
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(FRONTIERS IN MICROBIOLOGY, 2019-04-24)Acquisition and subsequent metabolism of different carbon and nitrogen sources have been shown to play an important role in virulence attributes of the fungal pathogen Aspergillus fumigatus, such as the secretion of host ...
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(ECOLOGY AND EVOLUTION, 2019-07)Birdsong has long been considered a sexually selected trait that relays honest information about male quality, and laboratory studies generally suggest that female songbirds prefer larger repertoires. However, analysis of ...