Browsing Interdisciplinary Sciences by Issue Date
Now showing items 1-20 of 22
-
(Nature Communications, 2019-05-01)SMARCB1 encodes the SNF5 subunit of the SWI/SNF chromatin remodeler. SNF5 also interacts with the oncoprotein transcription factor MYC and is proposed to stimulate MYC activity. The concept that SNF5 is a coactivator for ...
-
(Journal of Patient Experience, 2019-06)
-
(International Journal of Molecular Sciences, 2019-06-01)The PI3K/Akt pathway plays a crucial role in the survival, proliferation, and migration of macrophages, which may impact the development of atherosclerosis. Changes in Akt isoforms or modulation of the Akt activity levels ...
-
(Scientific Reports, 2019-07-15)To characterize cell types, cellular functions and intracellular processes, an understanding of the differences between individual cells is required. Although microscopy approaches have made tremendous progress in imaging ...
-
(Nature Communications, 2019-07-22)Severe respiratory syncytial virus (RSV) infection is a major cause of morbidity and mortality in infants <2 years-old. Here we describe that high-fiber diet protects mice from RSV infection. This effect was dependent on ...
-
(Scientific Reports, 2019-07-26)Methylmercury (MeHg) is an environmental neurotoxin with human exposure mainly from dietary intake of contaminated fish. Exposure to MeHg has been implicated in neurological damage, but research on its role in cancers, ...
-
(Biophysical Journal, 2019-08)Cardiolipin is an anionic lipid found in the mitochondrial membranes of eukaryotes ranging from unicellular microorganisms to metazoans. This unique lipid contributes to various mitochondrial functions, including metabolism, ...
-
(NATURE COMMUNICATIONS, 2019-08-02)Human memory is thought to depend on a circuit of connected brain regions, but this hypothesis has not been directly tested. We derive a human memory circuit using 53 case reports of strokes causing amnesia and a map of ...
-
(Scientific Reports, 2019-08-06)Reverse transcription polymerase chain reaction (RT-PCR) is the gold standard for the molecular diagnosis of many infectious diseases, including RNA viruses, but is generally limited to settings with access to trained ...
-
(Nature Communications, 2019-08-08)Drug hypersensitivity such as severe cutaneous adverse reactions (SCAR), including Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), could be life-threatening. Here, we enroll SCAR patients to investigate ...
-
(RSC Advances, 2019-08-18)The endoplasmic reticulum stress (ERS)-induced autophagy and apoptosis are favorable for the suppression of many cancer types. Salidroside (Salid) has been proven to be capable of inducing the apoptosis of many cancer ...
-
(BMC Public Health, 2019-12-30)Background: Data audits are often evaluated soon after completion, even though the identification of systematic issues may lead to additional data quality improvements in the future. In this study, we assess the impact of ...
-
(Value in Health, 2020-01)Objective: To evaluate the cost-effectiveness of multigene testing (CYP2C19, SLCO1B1, CYP2C9, VKORC1) compared with singlegene testing (CYP2C19) and standard of care (no genotyping) in acute coronary syndrome (ACS) patients ...
-
(Scand J Work Environ Health, 2022-10)Objectives Physically-demanding occupations may increase rotator cuff disease (RCD) risk and need for sur- gery. We linked a job-exposure matrix (JEM) to the UK Biobank cohort study to measure physical occupational exposures ...
-
(JAMA Oncology, 2022-11-17)IMPORTANCE Glioblastoma is the most lethal primary brain cancer. Clinical outcomes for glioblastoma remain poor, and new treatments are needed. OBJECTIVE To investigate whether adding autologous tumor lysate-loaded ...
-
(Jama Health Forum, 2022-11-18)IMPORTANCE The US Food and Drug Administration (FDA) has an accelerated approval program that has become the subject of scholarly attention and criticism, not only for the FDA's oversight of the program but also for its ...
-
(Journal of Lipid Research, 2022-12)The cumulative exposure to apolipoprotein B (apoB)-containing lipoproteins in the blood during early adult life is a central determinant of atherosclerotic cardiovascular disease risk. To date, the patterns and rates of ...
-
(Journal Of The American Heart Association, 2022-12-06)BackgroundPersons with HIV have a higher prevalence of coronary artery disease compared with their HIV-negative counterparts. Earlier identification of subclinical atherosclerosis may provide a greater opportunity for ...
-
(Biomedicine & Pharmacotherapy, 2022-12-06)Stomach cancer is a leading cause of cancer death. Helicobacter pylori is a bacterial gastric pathogen that is the primary risk factor for carcinogenesis, associated with its induction of inflammation and DNA damage. ...
-
(Frontiers In Aging Neuroscience, 2022-12-09)Many people with coronavirus disease 2019 (COVID-19) report varying degrees of memory impairment. Neuroimaging techniques such as MRI and PET have been utilized to shed light on how COVID-19 affects brain function in humans, ...