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Inhibition of MYC by the SMARCB1 tumor suppressor
(Nature Communications, 2019-05-01)
SMARCB1 encodes the SNF5 subunit of the SWI/SNF chromatin remodeler. SNF5 also interacts with the oncoprotein transcription factor MYC and is proposed to stimulate MYC activity. The concept that SNF5 is a coactivator for ...